2023-04-052023-04-052021766046https://doi.org/10.11606/issn.2176-7262.rmrp.2021.169851http://146.190.124.33/handle/123456789/5844Introduction: Obesity increases the risk of chronic non-communicable diseases (NCDs) and affects the course of diseases of infectious origin. Objective: Reviewing the literature on how obesity influences the severity of the clinical picture of some of the non-communicable and communicable diseases of greatest impact in Peru. Methods: Documentary research, from studies developed in various contexts associated with the presence of obesity along with infections or NCDs. Results: The condition of obesity reached by bad consumption habits and low physical activity is the main responsible for the high rate of NCDs, consequently, mortality. Conclusions: Excess weight affects the immune system, contributing specifically to exacerbated phenomena of a systemic inflammatory response, determined by increased secretion of adipocytokines, which predisposes the body to develop and contract NCDs and infectious diseases. © 2021 Faculdade de Medicina de Ribeirao Preto - U.S.P.. All rights reserved.enginfo:eu-repo/semantics/article