2023-04-052023-04-05202116659201https://doi.org/10.24875/j.gamo.21000023http://146.190.124.33/handle/123456789/6513The incidence of synchronous primary liver malign neoplasm is extremely low. We report a case of a 59 years old woman with Hepatitis B without surveillance, who was hospitalized for an incidental finding of 2 liver neoplasm. The patient underwent surgery (liver segmentectomy VII and VIII) and the pathology report described primary Hepatocarcinoma and primary Cholangiocarcinoma. The chronic hepatitis B increase the risk of malign primary liver neoplasm; thus, these patients should be regularly evaluated with image studies. © 2021 Publicaciones Permanyer. All rights reserved.spaHepatocarcinoma y colangiocarcinoma en nódulos separados. Reporte de caso y revisión de literatura [Hepatocarcinoma and cholangiocarcinoma in separate nodules. Case report and literatura review]info:eu-repo/semantics/article