2023-04-052023-04-05202125163507https://doi.org/10.29333/ejgm/10867http://146.190.124.33/handle/123456789/6295Coronavirus disease 2019 (COVID-19) has caused more than 32 million cases and almost a million deaths. Recent reviews have evidenced the role of hypertension in prognosis, nevertheless, its association with immunosuppression in COVID-19 context has not been studied. It was performed a cross-sectional analysis of a large Mexican population with the infection (n= 681 890). Prevalence of immunosuppression and hypertension was 1.10% and 19.50%, respectively. The adjusted model evidenced that hypertension was significantly associated with immunosuppression (odds ratio=1.18, 95% CI=1.11-1.25). Further research in pathways that justify the association between hypertension and immunosuppression in COVID-19 patients is recommended. © 2021 by Author/s and Licensed by Modestum.enginfo:eu-repo/semantics/article