Hypertrophic pachymeningitis in a patient with ANCA negative granulomatosis with polyangiitis: a case report [Paquimeningitis hipertrófica en un paciente con granulomatosis con poliangeítis ANCA negativo: reporte de un caso]

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dc.date.accessioned2023-04-05T12:48:31Z
dc.date.available2023-04-05T12:48:31Z
dc.date.issued2020
dc.description.abstractGranulomatosis with polyangiitis (GPA) is a vasculitic disease with an infrequent involvement of the central nervous system. This can lead, in rare cases, to hypertrophic pachymeningitis (HP), which is characterized by inflammation and fibrosis that cause a thickening of dura mater. At present, it is crucial to consider GPA in the differential diagnosis of elderly patients with intracranial hypertension. The case is presented of a 60-year-old male with progressive severe headache, vomiting, and wasting syndrome. Physical examination showed pallor, weight loss, and unilateral papilloedema. A gadolinium-enhanced brain MRI scan showed sinusitis, chronic otomastoiditis, and hypertrophic pachymeningitis. Finally, a meningeal biopsy concluded a necrotising granulomatous vasculitis compatible with GPA. However, PR3- and MPO-ANCA were negative. After corticosteroid therapy was initiated, the patient had a favorable outcome during his hospital stay. © 2020 Asociación Colombiana de Reumatología
dc.identifier.issn1218123
dc.identifier.urihttps://doi.org/10.1016/j.rcreu.2019.06.003
dc.identifier.urihttp://146.190.124.33/handle/123456789/6413
dc.language.isoenges_ES
dc.publisherAsociacion Colombiana de Reumatologiaes_ES
dc.sourceJournal of Gerontology and Geriatrics; Vol. 70 Núm. 1
dc.titleHypertrophic pachymeningitis in a patient with ANCA negative granulomatosis with polyangiitis: a case report [Paquimeningitis hipertrófica en un paciente con granulomatosis con poliangeítis ANCA negativo: reporte de un caso]es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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