Prothrombin C20209T mutation in deep vein thrombosis: a case report

Vista sencilla de ítem
dc.contributor.authorMuñoz, M.es_ES
dc.contributor.authorVilos, C.es_ES
dc.contributor.authorCantín, M.es_ES
dc.date.accessioned6/22/2022 13:33
dc.date.accessioned2022-09-30T16:09:25Z
dc.date.available6/22/2022 13:33
dc.date.available2022-09-30T16:09:25Z
dc.date.issued2015
dc.description.abstractThrombophilias is a recognized risk factor for thrombotic events. The prothrombin variant G20210A gene mutation has been commonly examined using polymerase chain reaction (PCR). Currently, in many clinical laboratories, performing the PCR in real-time technique, which, in addition to identifying the G20210A mutation, makes possible the detection of other mutations in the 3'UTR of the prothrombin gene by melting curve analysis, due to the ability of this analysis to be amplicon-dependent (e.g., C20209T, C20221T and A20218G). We report the first case in Chile that describes the atypical prothrombin C20209T mutation, in a 50-year-old male patient diagnosed with deep vein thrombosis in the lower limb and family history of thrombophilia. In the literature, there are few studies of the prevalence and functionality of this mutation; its association with thrombotic events is controversial. © 2015 E-Century Publishing Corporation. All rights reserved.es_ES
dc.formatapplication/pdfes_ES
dc.identifier.urihttps://pmc.ncbi.nlm.nih.gov/articles/PMC4565311/es_PE
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/26379928/es_PE
dc.identifier.urihttps://www.biochemia-medica.com/en/journal/24/1/10.11613/BM.2014.018es_PE
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/26379928/es_PE
dc.language.isoenges_ES
dc.publisherE-Century Publishing Corporationes_ES
dc.rightsinfo:eu-repo/semantics/closedAccesses_ES
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_ES
dc.sourceInternational Journal of Clinical and Experimental Medicinees_ES
dc.subjectBiochemistry, Genetics and Molecular Biologyes_ES
dc.subjectMedicinees_ES
dc.subject.ocdehttp://purl.org/pe-repo/ocde/ford#1.06.03es_ES
dc.titleProthrombin C20209T mutation in deep vein thrombosis: a case reportes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
77. Prothrombin C20209T mutation in deep vein thrombosis_A case report.pdf
Tamaño:
405.84 KB
Formato:
Adobe Portable Document Format
Descargar
Colecciones
Artículo