Achievement of the 2019 European Alliance of Associations for Rheumatology/American College of Rheumatology Criteria for Systemic Lupus Erythematosus and Amount of Damage Accrual: results from a multiethnic multicenter cohort
| dc.date.accessioned | 2023-04-05T12:48:10Z | |
| dc.date.available | 2023-04-05T12:48:10Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Objective: To determine the difference in outcomes in patients who achieved or did not achieve the 2019 European Alliance of Associations for Rheumatology (EULAR)/American College of Rheumatology (ACR) criteria. Methods: Patients from the LUpus in MInorities, NAture versus nurture (LUMINA) cohort were included. For these analyses, we compared those patients who achieved the 2019 EULAR/ACR criteria any time during follow-up to those who did not. The predefined outcomes were the last Systemic Lupus International Collaborating Clinics/ACR Damage Index (SDI) scores and survival. Univariable and multivariable negative binomial regression models were performed; adjustment models were based on a forward selection process. Results: In total, 98 of 640 patients never achieved the 2019 EULAR/ACR criteria. There was no difference in mean baseline SDI score among the patients who did not achieve the criteria compared to those who did. Conversely, the mean ± SD SDI score at last visit was lower for those who never achieved the criteria (1.2 ± 1.7 versus 2.0 ± 2.3, P = 0.0004). In the final adjusted model, the SDI score at last visit was 31% lower for those who never achieved the criteria (P = 0.0077). These patients were also more likely to survive, but this was not statistically significant. Conclusion: In our cohort, patients who did not achieve the 2019 EULAR/ACR criteria accrued less damage, suggesting that these criteria could allow us to identify a subset of patients with more severe disease than allowed by previous criteria. © 2020, American College of Rheumatology | |
| dc.identifier.issn | 2151464X | |
| dc.identifier.uri | https://doi.org/10.1002/acr.24213 | |
| dc.identifier.uri | http://146.190.124.33/handle/123456789/6253 | |
| dc.language.iso | eng | es_ES |
| dc.publisher | John Wiley and Sons Inc | es_ES |
| dc.source | Revista Española de Cirugía Oral y Maxilofacial; Vol. 41 Núm. 2 | |
| dc.title | Achievement of the 2019 European Alliance of Associations for Rheumatology/American College of Rheumatology Criteria for Systemic Lupus Erythematosus and Amount of Damage Accrual: results from a multiethnic multicenter cohort | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.type.version | info:eu-repo/semantics/publishedVersion |