Resistencia a nitrofuranos en Salmonella enterica aisladas de carne para consumo humano [Nitrofuran resistance in Salmonella enterica isolated from meat for human consumption]

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dc.date.accessioned2023-04-05T12:45:46Z
dc.date.available2023-04-05T12:45:46Z
dc.date.issued2020
dc.description.abstractThe mechanisms of resistance to nitrofurans from 18 meat samples with Salmonella enterica (chicken: 15; beef: 2; pork: 1) collected in Lima (Peru) were analyzed. The isolates were serotyped and the susceptibility levels to furazolidone and nitrofurantoin [with and without the efflux pump inhibitor Phenyl-Arginine-β-naphthylamide (PAβN)], the presence of mutations in the snrA and cnr genes and the transferability of resistance by conjugation were established. Fifteen samples with S. infantis (13 from chicken samples), 2 with S. enteritidis and 1 with S. anatum were identified. All isolates except the S. anatum were resistant to both nitrofurans showing MICs (minimum inhibitory concentration) of furazolidone and nitrofurantoin of 32-64 μg/mL and 128-256 μg/mL, respectively. The addition of PAßN had no effect on the MIC levels. All nitrofuran-resistant isolates showed amino acid codon alterations at both snrA and cnr (S. infantis: snrA STOP-151; cnr STOP-137; S. enteritidis: snrA STOP-180; cnr STOP-179). No transferable mechanisms of nitrofuran resistance were detected. © 2020, Instituto Nacional de Salud. All rights reserved.
dc.identifier.issn17264634
dc.identifier.urihttps://doi.org/10.17843/rpmesp.2020.371.4745
dc.identifier.urihttp://146.190.124.33/handle/123456789/5814
dc.language.isospaes_ES
dc.publisherInstituto Nacional de Saludes_ES
dc.sourceResearch in Veterinary Science; Vol. 144
dc.titleResistencia a nitrofuranos en Salmonella enterica aisladas de carne para consumo humano [Nitrofuran resistance in Salmonella enterica isolated from meat for human consumption]es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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