Eficacia antiinflamatoria tópica de Plantago major (llantén) vs. diclofenaco en ratas albinas
Fecha
2018
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ISSN de la revista
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Editor
Universidad Nacional Pedro Ruiz Gallo
Resumen
Este estudio buscó determinar la eficacia antiinflamatoria del gel de Plantago major al 20% en comparación con el gel de diclofenaco al 1% aplicado tópicamente en ratas albinas. Se realizó un estudio experimental con 24 ratas divididas en tres grupos, a las que se indujo inflamación con carragenina al 10% y se les aplicó los tratamientos correspondientes. Se analizaron los tiempos de desaparición de signos clínicos y los niveles de proteína C reactiva (PCR). Los resultados mostraron que el gel de diclofenaco al 1% fue más eficaz clínicamente en reducir los signos de inflamación, aunque el gel de Plantago major al 20% mostró una eficacia antiinflamatoria significativa en comparación con el placebo.
Abstract This study aimed to determine the anti-inflammatory efficacy of 20% Plantago major gel compared to 1% diclofenac gel applied topically in albino rats. An experimental study was conducted with 24 rats divided into three groups, where inflammation was induced with 10% carrageenan and the respective treatments were applied. Clinical sign disappearance times and C-reactive protein (CRP) levels were statistically analysed. Results showed that 1% diclofenac gel was clinically more effective in reducing inflammation signs, although 20% Plantago major gel demonstrated significant anti-inflammatory efficacy compared to the placebo.
Abstract This study aimed to determine the anti-inflammatory efficacy of 20% Plantago major gel compared to 1% diclofenac gel applied topically in albino rats. An experimental study was conducted with 24 rats divided into three groups, where inflammation was induced with 10% carrageenan and the respective treatments were applied. Clinical sign disappearance times and C-reactive protein (CRP) levels were statistically analysed. Results showed that 1% diclofenac gel was clinically more effective in reducing inflammation signs, although 20% Plantago major gel demonstrated significant anti-inflammatory efficacy compared to the placebo.
Descripción
Universidad Nacional Pedro Ruiz Gallo, Facultad de Medicina Humana. Tesis para optar el título profesional de Médico Cirujano.
Asesor Dr. Alfredo Chiclayo Padilla
Asesor Dr. Alfredo Chiclayo Padilla
Palabras clave
Medicina Natural, Medicina alternativa