Colistin resistance in multidrug-resistant Klebsiella pneumoniae strains at a perinatal maternal Institute in Lima, Peru, 2015-2018 [Resistencia a la colistina en cepas de Klebsiella pneumoniae multidrogorresistente del período 2015-2018 en un Instituto Materno Perinatal de Lima, Perú]
| dc.date.accessioned | 2023-04-05T12:45:36Z | |
| dc.date.available | 2023-04-05T12:45:36Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | The objective of this study was to evaluate the presence of colistin-and carbapenemic-resistant genes in multidrug-resistant Klebsiella pneumoniae strains isolated at the Instituto Materno Perinatal de Lima (2015-2018). Susceptibility levels were analyzed by disk diffusion and microdilution. The presence of colistin-and carbapenemic-resistant genes was determined by polymerase chain reaction (PCR) and was related to clonality. A total of 36 K. pneumoniae strains were analyzed, 5 (13.8%) were resistant to colistin and belonged to different clonal groups. Only 2 strains were found with carbapenemases (blaKPC and blaNDM), and no colistin plasmid genes were detected. High resistance levels to the other tested antimicrobials were observed, except for amikacin (13.9%). The results highlight the presence of colistinresistant strains (33.3% in 2018), a worrying situation as they are part of the latest treatment alternatives for infections caused by multiresistant pathogens. © 2020, Instituto Nacional de Salud. All rights reserved. | |
| dc.identifier.issn | 17264634 | |
| dc.identifier.uri | https://doi.org/10.17843/rpmesp.2020.374.5422 | |
| dc.identifier.uri | http://146.190.124.33/handle/123456789/5701 | |
| dc.language.iso | spa | es_ES |
| dc.publisher | Instituto Nacional de Salud | es_ES |
| dc.source | Advances in Gerontology; Vol. 11 Núm. 3 | |
| dc.title | Colistin resistance in multidrug-resistant Klebsiella pneumoniae strains at a perinatal maternal Institute in Lima, Peru, 2015-2018 [Resistencia a la colistina en cepas de Klebsiella pneumoniae multidrogorresistente del período 2015-2018 en un Instituto Materno Perinatal de Lima, Perú] | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.type.version | info:eu-repo/semantics/publishedVersion |