Actividad gastroprotectora y antisecretora de los compuestos fenólicos aislados de las hojas de Juglans neotropica Diels “nogal”. Ayacucho 2017
Date
2017
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad Nacional de San Cristóbal de Huamanga
Abstract
El estudio evaluó la actividad gastroprotectora y antisecretora de los compuestos fenólicos aislados de las hojas de Juglans neotropica Diels "nogal" en cobayos. Se realizaron experimentos en siete grupos de animales, incluyendo un grupo control y grupos tratados con diferentes dosis de los compuestos fenólicos. La dosis de 2,0 mg/kg mostró la mayor actividad gastroprotectora, con un 96,8% de inhibición de úlceras y un índice de ulceración media de 0,3. No se observó actividad antisecretora significativa.
Se concluyó que los compuestos fenólicos de Juglans neotropica tienen actividad gastroprotectora.
Abstract The study evaluated the gastroprotective and antisecretory activity of phenolic compounds isolated from the leaves of Juglans neotropica Diels "nogal" in guinea pigs. Experiments were conducted with seven groups of animals, including a control group and groups treated with different doses of the phenolic compounds. The 2.0 mg/kg dose showed the highest gastroprotective activity, with 96.8% ulcer inhibition and a mean ulcer index of 0.3. No significant antisecretory activity was observed. It was concluded that the phenolic compounds from Juglans neotropica have gastroprotective activity.
Abstract The study evaluated the gastroprotective and antisecretory activity of phenolic compounds isolated from the leaves of Juglans neotropica Diels "nogal" in guinea pigs. Experiments were conducted with seven groups of animals, including a control group and groups treated with different doses of the phenolic compounds. The 2.0 mg/kg dose showed the highest gastroprotective activity, with 96.8% ulcer inhibition and a mean ulcer index of 0.3. No significant antisecretory activity was observed. It was concluded that the phenolic compounds from Juglans neotropica have gastroprotective activity.
Description
Universidad Nacional de San Cristóbal de Huamanga. Facultad de Ciencias de la Salud. Escuela Profesional de Farmacia y Bioquímica. Tesis para obtener el título profesional de Químico Farmacéutico
Asesor Dr. Johnny Aldo Tinco Jayo
Asesor Dr. Johnny Aldo Tinco Jayo
Keywords
Actividad Gastroprotectora, Antisecreción, Compuestos Fenolicos, Juglans Neotropica Diels, Medicina tradicional, Enfermedad Gastrointestinal, Perú (Ayacucho)