Reporte de caso de resistencia al ganciclovir en enfermedad por citomegalovirus postrasplante cardiaco [Resistance to ganciclovir in cytomegalovirus infection after heart transplant: case report]
dc.contributor.author | Rojas-Contreras, C. | es_ES |
dc.contributor.author | De La Cruz-Ku, G. | es_ES |
dc.contributor.author | Vilcarromero, S. | es_ES |
dc.contributor.author | Villacaqui Ayllon, R. | es_ES |
dc.contributor.author | Valcarcel-Valdivia, B. | es_ES |
dc.date.accessioned | 6/22/2022 13:33 | |
dc.date.accessioned | 2022-09-30T16:54:31Z | |
dc.date.available | 6/22/2022 13:33 | |
dc.date.available | 2022-09-30T16:54:31Z | |
dc.date.issued | 2018 | |
dc.description.abstract | Cytomegalovirus infection after a heart transplant is a recurrent medical condition. Its frequency increases when the donors are serum-positive, and the recipients are serum-negative to this virus. In the pediatric population, the infection only develops in a small percentage and the patients rarely present resistance to conventional treatment with ganciclovir and valganciclovir. We presented the first report of a pediatric case of the cytomegalovirus infection resistant to ganciclovir and valganciclovir after a heart transplant in a Peruvian public hospital with an unusual presentation. The resistance to these drugs was evident after 277 days of evolution of the disease considering the non-remission of the symptomatology and the persistence of an elevated viral load. The administration of foscarnet led to a clinical and laboratory improvement until remission of the disease. © 2018, Instituto Nacional de Salud. All rights reserved. | es_ES |
dc.format | application/pdf | es_ES |
dc.identifier.doi | 10.17843/rpmesp.2018.351.3562 | es_ES |
dc.identifier.uri | https://doi.org/10.17843/rpmesp.2018.351.3562 | |
dc.language.iso | spa | es_ES |
dc.publisher | Instituto Nacional de Salud | es_ES |
dc.rights | info:eu-repo/semantics/closedAccess | es_ES |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | es_ES |
dc.source | Revista Peruana de Medicina Experimental y Salud Pública | es_ES |
dc.subject | Medicine | es_ES |
dc.subject.ocde | http://purl.org/pe-repo/ocde/ford#3.00.00 | es_ES |
dc.title | Reporte de caso de resistencia al ganciclovir en enfermedad por citomegalovirus postrasplante cardiaco [Resistance to ganciclovir in cytomegalovirus infection after heart transplant: case report] | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |