Epidemiology of systemic lupus erythematosus

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dc.contributor.authorPons-Estel G.J.es_ES
dc.contributor.authorUgarte-Gil, M.F.es_ES
dc.contributor.authorAlarcón, G.S.es_ES
dc.date.accessioned6/22/2022 13:33
dc.date.accessioned2022-09-30T16:31:53Z
dc.date.available6/22/2022 13:33
dc.date.available2022-09-30T16:31:53Z
dc.date.issued2017
dc.description.abstractIntroduction: Systemic lupus erythematosus (SLE) is a disease distributed worldwide, which occurs in both genders, and across racial/ethnic and age groups; however, higher rates are observed in adults, in women and in non-Caucasians. Genetic, environmental, sociodemographic and methodological issues are responsible not only for these differences but for the variable course and outcome of the disease. Non-Caucasians have a more severe disease with a higher risk for early mortality and damage accrual. Males also have a more severe disease; however, a negative impact of male gender on lupus outcomes has not been firmly established. Childhood-onset is associated with a more severe disease; moreover, it is also associated with higher damage and diminished survival; finally, late-onset lupus is mild but it is associated with higher damage accrual and a diminished survival. Areas covered: In this review, we discuss the incidence and prevalence of SLE, the impact of age, gender and race/ethnicity in SLE and in the survival of those affected. Expert commentary: Age, gender and race/ethnicity impact disease expression in SLE patients; despite improvements in survival, mortality in SLE remains almost three times higher than in the general population. © 2017 Informa UK Limited, trading as Taylor & Francis Group.es_ES
dc.formatapplication/pdfes_ES
dc.identifier.doi10.1080/1744666X.2017.1327352es_ES
dc.identifier.urihttps://doi.org/10.1080/1744666X.2017.1327352
dc.language.isoenges_ES
dc.rightsinfo:eu-repo/semantics/closedAccesses_ES
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_ES
dc.sourceExpert Review of Clinical Immunologyes_ES
dc.subjectImmunology and Microbiologyes_ES
dc.subjectMedicinees_ES
dc.subject.ocdehttp://purl.org/pe-repo/ocde/ford#3.01.03es_ES
dc.titleEpidemiology of systemic lupus erythematosuses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
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