Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals [Diagnóstico del Síndrome de Guillain-Barré y uso de los criterios de Brighton en hospitales Peruanos]

dc.date.accessioned2023-04-05T12:47:59Z
dc.date.available2023-04-05T12:47:59Z
dc.date.issued2022
dc.description.abstractBackground: Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system that caused multiple epidemiological outbreaks in Peru during 2018 and 2019. It is usually diagnosed using the Brighton criteria (BC). Objective: We aimed to determine the performance of Peruvian neurologists in diagnosing GBS based on the BC, along with its associated factors. Methods: This was a retrospective multicenter cohort study. We included patients diagnosed with GBS between 2007 and 2018 in three public hospitals in Lima, Peru. We collected data regarding demographic, clinical and management characteristics. We evaluated the use of the BC for confirmatory diagnosis of GBS and developed a logistic regression model to identify factors associated with its use. Results: Out of 328 cases, we reviewed 201 available charts. The median age was 48 years, with male predominance. Over half of the patients presented an inadequate motor examination according to their Medical Research Council (MRC) score. Additional testing included lumbar puncture and electrophysiological testing, in over 70% of the cases. The BC showed certainty level 1 in 13.4% and levels 2 and 3 in 18.3%. Neither the quality of the motor examination nor the type of institution showed any association with the BC. Conclusions: Level 1 diagnostic certainty of the BC was met in less than one quarter of the cases with a GBS diagnosis in three centers in Lima, Peru, between 2007 and 2018. This level was not significantly associated with being treated in a specialized institute, rather than in a general hospital. © 2022 Associacao Arquivos de Neuro-Psiquiatria. All rights reserved.
dc.identifier.issn0004282X
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/35946711/es_PE
dc.identifier.urihttps://cris.cientifica.edu.pe/es/publications/diagn%C3%B3stico-del-s%C3%ADndrome-de-guillain-barr%C3%A9-y-uso-de-los-criterioses_PE
dc.identifier.urihttps://pmc.ncbi.nlm.nih.gov/articles/PMC9387192/es_PE
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85135733785&partnerID=8YFLogxKes_PE
dc.language.isoenges_ES
dc.publisherAssociacao Arquivos de Neuro-Psiquiatriaes_ES
dc.sourceRevista de Investigaciones Veterinarias del Perú; Vol. 31 Núm. 3
dc.titleDiagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals [Diagnóstico del Síndrome de Guillain-Barré y uso de los criterios de Brighton en hospitales Peruanos]es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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