Asociación entre resistencia a la insulina y proteína C reactiva en una muestra de peruanos no obesos [Association between insulin resistance and C-reactive protein in a sample of non-obese Peruvians]

dc.date.accessioned2023-04-05T12:48:15Z
dc.date.available2023-04-05T12:48:15Z
dc.date.issued2021
dc.description.abstractBackground: The role of insulin resistance (IR) in chronic disease is largely due to the presence of low-grade inflammation, through proteins such as C-reactive protein (CRP). Although there is evidence of a relationship between IR and CRP, this is scarce in non-obese population. Objective: To evaluate the association between IR and CRP in a sample of non-obese Peruvians. Material and methods: Cross-sectional analytical study of the secondary database of the PERU MIGRANT study. Results: We found a prevalence of IR of 3.72 %; while the prevalence of high CRP (≥ 3 mg/L) in the study subjects was 19.26 %. Patients with high CRP had 5.65 % higher frequency of having RI, compared to those with normal CRP (2.63 % vs 8.28 %; p= 0.003). Females had 1.49 % higher frequency of having IR, compared to males (4.51 % vs. 3.02 %; p= 0.336). Patients with high CRP had 214% higher frequency of having IR, compared to those without high CRP (PR=3.14, 95%CI: 1.52 - 6.50) and adjusting for confounding covariates (sex, age, BMI, group, smoking status, alcohol drinker and physical activity) high CRP had 198% higher frequency of having IR, compared to those without high CRP (PR=2.98, 95%CI: 1.49 - 5.96). Conclusions: In non-obese patients, the presence of CRP, in the absence of infectious pathology, could imply the existence of IR. © 2021 Medical Body of the Almanzor Aguinaga Asenjo National Hospital. All rights reserved.
dc.identifier.issn22255109
dc.identifier.urihttp://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S2227-47312021000200002es_PE
dc.identifier.urihttps://hdl.handle.net/20.500.12867/5138es_PE
dc.identifier.urihttps://pesquisa.bvsalud.org/gim/resource/ru/biblio-1354910es_PE
dc.identifier.urihttps://doi.org/10.35434/rcmhnaaa.2021.142.1021es_PE
dc.language.isospaes_ES
dc.publisherMedical Body of the Almanzor Aguinaga Asenjo National Hospitales_ES
dc.sourceZootaxa; Vol. 4526 Núm. 2
dc.titleAsociación entre resistencia a la insulina y proteína C reactiva en una muestra de peruanos no obesos [Association between insulin resistance and C-reactive protein in a sample of non-obese Peruvians]es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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