Estudio comparativo de plantas hepatoprotectoras de origen chino y peruano
Fecha
2017
Autores
Título de la revista
ISSN de la revista
Título del volumen
Editor
Universidad Inca Garcilaso de la Vega
Resumen
El objetivo de esta investigación fue establecer las diferencias y semejanzas entre las plantas hepatoprotectoras de origen chino y peruano, y reconocer los metabolitos secundarios responsables del efecto hepatoprotector. Se utilizaron métodos de tamizaje fitoquímico y cromatografía en capa fina (CCF). Los metabolitos secundarios más frecuentes en los extractos hidroalcohólicos fueron derivados terpénicos (12%), flavonoides (10%) y alcaloides (9%). Los Rf hallados en la CCF variaron entre las plantas chinas y peruanas, destacando la presencia de derivados terpénicos, flavonoides y glicósidos amargos. Se concluyó que existen semejanzas en las concentraciones de metabolitos secundarios y en la tipología de las plantas hepatoprotectoras chinas y peruanas, atribuyendo el efecto hepatoprotector a estos metabolitos.
Abstract The objective of this research was to establish the differences and similarities between hepatoprotective plants of Chinese and Peruvian origin, and to identify the secondary metabolites responsible for the hepatoprotective effect. Phytochemical screening and thin-layer chromatography (TLC) methods were used. The most frequent secondary metabolites in the hydroalcoholic extracts were terpenoid derivatives (12%), flavonoids (10%), and alkaloids (9%). The Rf values found in the TLC varied between Chinese and Peruvian plants, highlighting the presence of terpenoid derivatives, flavonoids, and bitter glycosides. It was concluded that there are similarities in the concentrations of secondary metabolites and in the typology of Chinese and Peruvian hepatoprotective plants, attributing the hepatoprotective effect to these metabolites.
Abstract The objective of this research was to establish the differences and similarities between hepatoprotective plants of Chinese and Peruvian origin, and to identify the secondary metabolites responsible for the hepatoprotective effect. Phytochemical screening and thin-layer chromatography (TLC) methods were used. The most frequent secondary metabolites in the hydroalcoholic extracts were terpenoid derivatives (12%), flavonoids (10%), and alkaloids (9%). The Rf values found in the TLC varied between Chinese and Peruvian plants, highlighting the presence of terpenoid derivatives, flavonoids, and bitter glycosides. It was concluded that there are similarities in the concentrations of secondary metabolites and in the typology of Chinese and Peruvian hepatoprotective plants, attributing the hepatoprotective effect to these metabolites.
Descripción
Universidad Inca Garcilaso de la Vega, Facultad de Ciencias Farmacéuticas y Bioquímica. Tesis para optar el título profesional de Químico Farmacéutico y Bioquímico.
Asesora Dra. Q. F. Nancy Chávez Velásquez
Asesora Dra. Q. F. Nancy Chávez Velásquez
Palabras clave
Cromatografía, Metabolitos Secundarios, Extractos Hidroeólicos, Plantas medicinales