Launching of the Anaemia Research Peruvian Cohort (ARPEC): a multicentre birth cohort project to explore the iron adaptive homeostasis, infant growth and development in three Peruvian regions

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dc.contributor.authorMontag, Doreenes_ES
dc.contributor.authorDelgado, Carlos A.es_ES
dc.contributor.authorQuispe, Consueloes_ES
dc.contributor.authorWareham, Davides_ES
dc.contributor.authorGallo, Valentinaes_ES
dc.contributor.authorSanchez-Choy, Josées_ES
dc.contributor.authorSánchez, Victores_ES
dc.contributor.authorAnaya, Ruthes_ES
dc.contributor.authorFlores, Elainees_ES
dc.contributor.authorRoca, Lorenaes_ES
dc.contributor.authorMamani Urrutia, Víctor Alfonsoes_ES
dc.contributor.authorRivera Medina, Juanes_ES
dc.contributor.authorVelasquez, Pabloes_ES
dc.contributor.authorÁguila, Carlos deles_ES
dc.contributor.authorPrendergast, Andrewes_ES
dc.contributor.authorPalomino, Julioes_ES
dc.date.accessioned2023-04-12T12:30:17Z
dc.date.available2023-04-12T12:30:17Z
dc.date.issued2021
dc.description.abstractBackground: Preventing infantile anaemia and ensuring optimal growth and development during early childhood, particularly in resource-constrained settings, represent an ongoing public health challenge. Current responses are aligned to treatment-based solutions, instead of determining the roles of its inter-related causes. This project aims to assess and understand the complex interplay of eco-bio-social-political factors that determine infantile anaemia to inform policy, research design and prevention practices. Methods: This is a longitudinal birth cohort study including four components: (1) biological, will assess known blood markers of iron homeostasis and anaemia and stool microbiota to identify and genetically analyse the participants’ flora; (2) ecological, will assess and map pollutants in air, water and soil and evaluate features of nutrition and perceived food security; (3) social, which will use different qualitative research methodologies to explore key stakeholders and informants’ perceptions related to nutritional, environmental and anaemia topics, participant observations and a participatory approach and (4) a political analysis, to identify and assess the impact of policies, guidelines and programmes at all levels for infantile anaemia in the three regions. Finally, we will also explore the role of social determinants and demographic variables longitudinally for all study participants. This project aims to contribute to the evidence of the inter-related causal factors of infantile anaemia, addressing the complexity of influencing factors from diverse methodological angles. We will assess infantile anaemia in three regions of Peru, including newborns and their mothers as participants, from childbirth until their first year of age. Ethics and dissemination: Ethical approval was obtained from the Institutional Research Ethics Committee of the Instituto Nacional de Salud del Niño (Lima, Peru), CIEI-043-2019. An additional opinion has been granted by the Ethical Committee of Queen Mary University of London (London, UK). Dissemination across stakeholders is taking part as a continues part of the research process.es_ES
dc.formatapplication/pdfes_ES
dc.identifier.doi10.1136/bmjopen-2020-045609
dc.identifier.urihttps://bmjopen.bmj.com/content/11/5/e045609
dc.identifier.urihttp://146.190.124.33/handle/123456789/6578
dc.language.isoenges_ES
dc.publisherBritish Medical Journales_ES
dc.relation.ispartofBMJ Open; Vol. 11, N° 5, e045609
dc.sourceBMJ Openes_ES
dc.subjectANEMIAes_ES
dc.subjectCOHORT STUDIESes_ES
dc.subjectPERÚes_ES
dc.titleLaunching of the Anaemia Research Peruvian Cohort (ARPEC): a multicentre birth cohort project to explore the iron adaptive homeostasis, infant growth and development in three Peruvian regionses_ES
dc.typeinfo:eu-repo/semantics/article
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