New leishmanicidal stilbenes from a peruvian folk medicine, Lonchocarpus nicou

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dc.contributor.authorFuchino, H.es_ES
dc.contributor.authorKiuchi, F.es_ES
dc.contributor.authorYamanaka, A.es_ES
dc.contributor.authorObu, A.es_ES
dc.contributor.authorWada, H.es_ES
dc.contributor.authorMori-Yasumoto, K.es_ES
dc.contributor.authorKawahara, N.es_ES
dc.contributor.authorFlores, D.es_ES
dc.contributor.authorPalacios, O.es_ES
dc.contributor.authorSekita, S.es_ES
dc.contributor.authorSatake, M.es_ES
dc.date.accessioned6/22/2022 13:33
dc.date.accessioned2022-09-30T16:49:28Z
dc.date.available6/22/2022 13:33
dc.date.available2022-09-30T16:49:28Z
dc.date.issued2013
dc.description.abstractTwo new stilbenes, 1 and 2, were isolated as leishmanicidal constituents from the methanolic extract of Lonchocarpus nicou leaves and stem, together with five known stilbenes and rotenoids. Their chemical structures were determined by spectral methods. Among them, the cis stilbene-type compounds 1 and 4 showed potent leishmanicidal activity (IC50: 5.5, 3.9μg/mL), while the trans stilbene-type compounds 2 and 5, and rotenoids 6 and 7, showed moderate activities (IC50: 9.9, 12.8, 22.6, 19.6μg/mL, respectively). © 2013 The Pharmaceutical Society of Japan.es_ES
dc.formatapplication/pdfes_ES
dc.identifier.doi10.1248/cpb.c13-00385es_ES
dc.identifier.urihttps://doi.org/10.1248/cpb.c13-00385
dc.language.isoenges_ES
dc.rightsinfo:eu-repo/semantics/closedAccesses_ES
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_ES
dc.sourceChemical and Pharmaceutical Bulletines_ES
dc.subjectChemistryes_ES
dc.subjectPharmacology, Toxicology and Pharmaceuticses_ES
dc.subject.ocdehttp://purl.org/pe-repo/ocde/ford#1.04.00es_ES
dc.titleNew leishmanicidal stilbenes from a peruvian folk medicine, Lonchocarpus nicoues_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
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