Estudio químico del liquen Umbilicaria calvescens Nyl
Date
2018
Authors
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Publisher
Universidad Nacional de Ingeniería
Abstract
Tradicionalmente, los líquenes se han utilizado como fuente de alimento, en medicina natural y para tintes. Actualmente, son importantes en la industria farmacéutica por sus propiedades antibacterianas, antioxidantes y anticancerígenas. Este estudio se centró en el análisis químico del liquen Umbilicaria calvescens Nyl., recolectado en Huaytapallana, Huancayo, Junín. Se realizó un análisis preliminar identificando metabolitos secundarios como aminogrupos, grupos fenólicos, taninos y triterpenoides/esteroides. Se aislaron los compuestos mayoritarios ácido úsnico y ácido lecanórico, identificados por su punto de fusión y espectros (EM, RMN1H, RMN13C, IR y UV). Estos compuestos se extrajeron con n-hexano y acetona y se purificaron mediante técnicas cromatográficas. El análisis cuantitativo del ácido úsnico mostró un 0.41% del compuesto.
Abstract Traditionally, lichens have been used as a food source, in natural medicine, and for dyes. Currently, they are significant in the pharmaceutical industry due to their antibacterial, antioxidant, and anticancer properties. This study focused on the chemical analysis of the lichen Umbilicaria calvescens Nyl., collected in Huaytapallana, Huancayo, Junín. A preliminary analysis identified secondary metabolites such as amino groups, phenolic groups, tannins, and triterpenoids/steroids. The major lichen compounds, usnic acid and lecanoric acid, were isolated and identified by their melting points and spectra (MS, 1H NMR, 13C NMR, IR, and UV). These compounds were extracted with n-hexane and acetone and purified using chromatographic techniques. The quantitative analysis of usnic acid showed a 0.41% content of the compound.
Abstract Traditionally, lichens have been used as a food source, in natural medicine, and for dyes. Currently, they are significant in the pharmaceutical industry due to their antibacterial, antioxidant, and anticancer properties. This study focused on the chemical analysis of the lichen Umbilicaria calvescens Nyl., collected in Huaytapallana, Huancayo, Junín. A preliminary analysis identified secondary metabolites such as amino groups, phenolic groups, tannins, and triterpenoids/steroids. The major lichen compounds, usnic acid and lecanoric acid, were isolated and identified by their melting points and spectra (MS, 1H NMR, 13C NMR, IR, and UV). These compounds were extracted with n-hexane and acetone and purified using chromatographic techniques. The quantitative analysis of usnic acid showed a 0.41% content of the compound.
Description
Universidad Nacional de Ingeniería Facultad de Ciencias. Tesis para obtener el título profesional de Licenciado en Química.
Asesor M.Sc. Elena Alicia Cóndor Cuyubamba
Asesor M.Sc. Elena Alicia Cóndor Cuyubamba
Keywords
Ácido Úsnico, Ácido Lecanórico, Líquenes