Characterization of Escherichia coli D7111 producing the β-Lactamase TEM-176 [Caracterización de Escherichia coli D7111 productora de β-Lactamasa TEM-176]

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dc.date.accessioned2023-04-05T12:46:10Z
dc.date.available2023-04-05T12:46:10Z
dc.date.issued2021
dc.description.abstractThe present report is the original description of blaTEM-176. The mechanisms of resistance to antimicrobial agents were determined in an enterotoxigenic Escherichia coli, determining the susceptibility to 22 antimicrobials classified in 15 different groups by agar diffusion and establishing the phylogenetic group, mechanisms of resistance and presence of Class 1 and 2 integrons. Integrons and β-lactam resistance genes were sequenced. The isolate, belonging to phylogenetic group A, showed the presence of resistance or diminished susceptibility to a ampicillin, amoxicillin plus clavulanic acid, nalidíxic acid, ciprofloxacin, streptomycin, kanamycin, tetracycline, trimethoprim, sulfisoxazole, cotrimoxazole, azithromycin and nitrofurantoin, carrying blaTEM, aadA1/2, aphA1, sul3, tet(A) and a Class 2 integron containing a dfrA1 gene. Quinolone resistance was related to the substitution Ser83 Ala. The TEM sequencing showed the presence of the new substitution Ala222 Val, which led to the description of the new β-lactamase blaTEM-176 . © 2021, Instituto Nacional de Salud. All rights reserved.
dc.identifier.issn17264634
dc.identifier.urihttps://doi.org/10.17843/rpmesp.2021.381.6727
dc.identifier.urihttp://146.190.124.33/handle/123456789/5998
dc.language.isospaes_ES
dc.publisherInstituto Nacional de Saludes_ES
dc.sourceRevista Brasileira de Epidemiologia; Vol. 24
dc.titleCharacterization of Escherichia coli D7111 producing the β-Lactamase TEM-176 [Caracterización de Escherichia coli D7111 productora de β-Lactamasa TEM-176]es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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