Examinando por Autor "Honaramooz, A."

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    Azoospermia and testicular hypoplasia in a boar carrier of a novel Y-autosome translocation
    (Karger, 2017) Villagómez, D. A. F.; Revay, T.; Donalson, B.; Rezaei, S.; Pinton A.; Palomino Cano, Jesús Manuel; Junaidi, A.; Honaramooz, A.; King, W. A.
    Few sex-autosome chromosome abnormalities have been documented in domestic animal species. In humans, Y-autosome chromosome abnormalities may occur at a rate of 1/2,000 live births, whereas in the domestic pig only 2 Y-autosome reciprocal translocations have been previously described. During a routine cytogenetic screening of young boars, we identified a new Y-autosome translocation carrier, which after puberty showed semen devoid of sperm and testicular hypoplasia with spermatogenesis arrest. Whole chromosome painting by FISH analysis corroborated the reciprocal nature of the chromosomal exchanges between the Y chromosome and SSC13. The possible causes for the observed meiotic arrest of the carrier are reviewed.